Phytochemical and antimicrobial evaluation of aqueous and organic extracts of calotropis procera ait leaf and latex. Antimicrobial activity and phytochemical analysis of calotropis gigantea root, latex extracts. Calotropis gigantea called swetarka and calotropis procera called raktarka. Pdf antimicrobial activity of akanda calotropis gigantea l. The aim of the present study was to screen leaves of calotropis gigantea for the antimicrobial activity. Asthma arachidonic acid calotropis gigantea ovalbumin 1. Calotropis procera, latex, antimicrobial, antioxidant, antifungal. An recent approach on calotropis gigantea and calotropis procera. Antimicrobial activity of latex silver nanoparticles. Latex extractables of calotropis gigantea sciencedirect. Pdf antimicrobial properties of ocimum sanctum and. All structured data from the file and property namespaces is available under the creative commons cc0 license. University rewa india nbri lucknow india abstract herbals plants are effective source of traditional and modern medicines, useful for primary health care.
Mudarol, the chief resinol component of the root bark ofcalotropis gigantea, has been separated into two isomeric compounds by fractional crystallisation of the acetates and also by chromatographic adsorption analysis of the free alcohols. It contains chemicals that can interfere with heart function, particularly at high doses. It is a very common herb seen widely throughout india. Chemical composition of calotropis gigantea springerlink. Studies on endophytic fungi of calotropis procera l.
Study on antibacterial activity of calotropis procera peerj preprints. The first species being abundant while the second being restricted to forest areas. Ethnomedicinal, pharmaceutical and pesticidal uses of calotropis. Calotropis gigantea is a common wasteland weed and known for various medicinal properties. Evaluation of antiinflammatory effect of calotropis gigantea and. Antifungal, antioxidant and antibacterial activities of calotropis procera mushtaq ahmed, rehmat ali khan, s. Shahzaib, abdullah khan, arif waqar zaif, wasim ahmed department of biotechnology, university of science and technology bannu, khyber pakhtunkhwa pakistan key words.
The antiinflammatory activity of low dose of the aqueous extract of t. Antioxidant activity of calotropis gigantea by dpph method antioxidant activity concentrati in % on gml root extract ascorbic acid 100 200 300 82. Flowers, in comparison with levamisole, was evaluated in a series of in vitro and in vivo studies. The latex of calotropis gigantea contains cardio glycosides, volatile fatty acids and calcium oxalate. The leaves are sessile and subsessile, opposite, ovate, cordate at the base.
Traditional knowledge and use of medicinal plants in the eastern desert of egypt. Article information, pdf download for pretreatment of calotropis. Aug 18, 2016 the aim of this investigation was to carry out the analysis of antibacterial and antifungal activities of different parts of calotropis gigantea. Pretreatment of calotropis gigantea fibers with functional. Antimicrobial activity of latex of calotropis gigantea against pathogenic microorganisms an in vitro study article pdf available in pharmacologyonline 3. Calotropis species recorded for a number of activities like. Pdf the antibacterial activity of methanol extract from the root bark of akanda calotropis. Antimicrobial activity of ethanol, methanol and chloroform extracts from flower, leaves and roots of c.
Therapeutic and biological activities of calotropis procera ait. Rn a h tcol eg f p rm cy,s ns mhowneemuch road, mandsaur m. Calotropis gigantea, the crown flower, is a species of calotropis native to cambodia, indonesia, malaysia, the philippines, citation needed thailand, sri lanka, india, china, pakistan, nepal, and tropical africa. Traditionally calotropis is used alone or with other medicinals caius 1986 to treat common. Preliminary phytochemical screening of calotropis gigantea leaf. Ocimum sanctum and calotropis gigantea leaves on clinical pathogens. Calotropis gigantea linn and tridax procumbens linn, are well documented medicinal plants.
Introduction the root of calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the indian literature. Widely it is used medicinally, to treat boils, infected wounds and other skin problems in people. Review article pharmacognostical aspects and pharmacological. Small trees or shrubs, these two species are native to southern asia and africa and were introduced to south america and the islands of the caribbean, where they have naturalized. As an important medicinal shrub and a fiber resource plant, there is an urgent need for developing molecular markers to facilitate breeding and genetic improvement of varieties. Calotropis procera is a well known plant and has been traditionally used for diarrhea, stomacic, sinus, fistula, and skin disease, alikhan and khanum 2005, raghubir et al. The ph of latex of these two species has been found different in the present study. Diabetes is the worlds largest endocrine disease with deranged carbohydrate, fats and protein metabolism. A study on phytochemical screening and invitro antioxidant. The highest activity diameter of zone of inhibition 26 mm was demonstrated by the ethanolic extract of c. In acetic acid induced writhing test, an inhibition of 20. Preliminary phytochemical screening of calotropis gigantea leaf suchita singh, sanchita singh, r. An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region in nepal, the latex is applied to sprains, body pains, boils and pimples.
The plant has oval, light green leaves and milky stem. Antioxidant, antimicrobial activities and gcms analysis of. Calotropis gigantea and calotropis procera are to a great extent having a very similar chemical properties, but the colours of their flowers are different. A downloadable pdf document of a book in prepublication awaiting illustration. Comparative study of plant extracts crude and aqueous, methanolic and ethanolic with antibiotics, provide evidence that calotropis procera extracts has the similar antibacterial activity as these antibiotics against test pathogens i.
Pdf the antimicrobial activity of crude aqueous extract of latex of calotropis gigantea apocynaceae was. Calotropis gigantea latex, antifungal activity, minimum fungicidal concentration, zone of inhibition, disc diffusion method correspondence to author. The compositions of the alkane fraction, total triterpene alcohol fraction, and free, acetyl. Antioxidant, antimicrobial activities and gcms analysis of calotropis gigantea white flowers shopna rajamohan, prabakaran kalaivanan, ilayaraja sivagnanam, manivannan rajamanickam abstract calotropis gigantea white asclepiadaceae, is a weed plant commonly known as giant milkweed. Pdf antimicrobial activity of latex of calotropis gigantea against. In residual film toxicity, methanol extract and its chloroform and petroleum ether fractions showed insecticidal activity against t. Antimicrobial activity of akanda calotropis gigantea l.
Antimicrobial activities of different parts of calotropis. Calotropis gigantea linn and its chloroform and petroleum ether 4060c soluble fractions were evaluated against several inster of larvae and adult of tribolium castaneum. Calotropis a medicinal plant of family asclepiadaceae has been utilized in ayurveda, unani, siddha and many other traditional systems to cure diseases. Calotropis gigantea arka uses, dose, side effects, ayurveda. Proteins exhibiting distinct activities and displaying antimicrobial properties have. This page was last edited on 8 january 2016, at 11. The root and latex of calotropis gigantea were screened for its antimicrobial and phytochemical activities. Insecticidal activity of root bark of calotropis gigantea l.
The hexane and methanol soluble extract of the latex coagulum of calotropis gigantea afforded two new triterpene esters, viz. The in vitro studies demonstrated the anthelmintic effects p of crude aqueous cae and crude methanolic extracts cme of calotropis procera. In 1980, pal and sinha had isolated, crystallized and studied the properties of calotropins d1 and d2 from c. The alcoholic extract of the flowers of calotropis gigantea was administered orally and explored for its analgesic activity in chemical and thermal models in mice. Asclepiadaceae a wildly growing plant has been reported to possess number of medicinal properties 8 and other purposes 9. Antimicrobial properties of calotropis procera ait. Asclepiadaceae has been known to the traditional systems of medicine and plant known as madar in unani medicinal system. Study on antibacterial activity of calotropis procera peerj. In this study, using the illumina high throughput sequencing. Studies on antidiarrheal activity of calotropis gigantea r. The agar diff usion test was used to check the antimicrobial activity of the hexane and ethanolic.
The aim of the present study was to screen leaves of calotropis gigantea for the antimicrobial activity against clinical isolates of bacteria. Pdf antidiabetic activity of calotropis gigantea in. Giganteol which was first obtained from the stem bark is one of them and a new triterpene alcohol, isogiganteol is the other. The analysis of antimicrobial activity of aqueous, methanolic and ethanolic extract of leaves and flower of calotropis procera was carried out in. Ramesh chandra have proved calotropis gigantea is having a significant anti diarrheal activity against castor oil induced diarrhea. Other articles where calotropis gigantea is discussed. Free radical scavenging activity of calotropis species. Antifungal, antioxidant and antibacterial activities of. Research article studies on anticonvulsant activity of stem. Inhibitory effect of calotropis gigantea extract on ovalbumin. Biological morphology and ethanopharmocological importance. Wound healing activity of latex of calotropis gigantea narendra nalwaya1, gaurav pokharna1, lokesh deb2, naveen kumar jain1 phone no. The results of the in vitro antifungal assay revealed that the growths of fungal strains were affected by the latex extract by forming clear. To evaluate the antivenom activity of calotropis gigantea plantextract against vipera russelli snake venom.
Sep 22, 2015 the sodom apple calotropis gigantea, a member of the asclepiadaceae family, is a large evergreen shrub native to continental asia and northern africa. However, users may print, download, or email articles for individual use. Antimicrobial activity and phytochemical analysis of. The cytotoxic potential of stem organic extracts from calotropis procera. Antifertility activity the effect of an ethanolic extract of the roots of calotropis procera has been studied in albino rats to explore its antifertility and hormonal activities. Antimicrobial activity of latex of calotropis gigantea against pathogenic microorganisms an in vitro study gaurav kumar, loganathan karthik and kokati venkat bhaskara rao molecular and microbiology research lab, environmental biotechnology division, school of bio science and technology, vit university, vellore632 014, tamil nadu, india. Calotropis is used as a traditional medicinal plant with unique properties.
In vitro and in vivo antiproliferative activity of calotropis procera stem. Anthelmintic activity the anthelmintic activity of calotropis procera linn. It can cause serious side effects including vomiting, diarrhea, slow heartbeat, convulsions, and death. Antibacterial activity of aqueous extract of calotropis. It is widely used in many ayurvedic treatments, both externally ksharasutra and internally. Calotropis gigantea is usedtraditionally to treat common diseases such as fever, rheumatism, indigestion, cough, cold, eczema, asthma, elephantiasis, nausea, vomiting and diarrhoea, either alone or with other medicinesaim of the study. The latex of calotropis procera was collected from the aerial parts of the wild. Calotropis gigantea white asclepiadaceae, is a weed plant commonly. Calotropis procera possesses antinociceptive activity, which is independent of the opioid system s aber et al. Files are available under licenses specified on their description page. Calotropis gigantea grows to a height of 8 to 10 ft 2. Ethnomedicine, phytochemistry and pharmacology of calotropis. Antioxidant, antimicrobial activities and gcms analysis.
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